2010年6月17日 星期四
2010年6月9日 星期三
2010年3月25日 星期四
2010年3月24日 星期三
吳孟澤醫師經歷
現職: 中國醫藥大學醫學系皮膚學科副教授/科主任
中國醫藥大學附設醫院皮膚科主治醫師/科主任
出生地: 嘉義市
研究興趣與方向: 皮膚科學, 雷射光療, 幹細胞再生醫學, 色素醫學 (白斑黑斑), 免疫疾病診療, 癌症診療
學歷:
1992 高雄醫學院醫學士
1997 高雄醫學院醫學研究所醫學碩士
2002 高雄醫學大學醫學研究所醫學博士
研究職務經歷:
1999-2001 美國國家衛生院國家癌症中心博士後研究
Visiting Fellow, National Cancer Institute,
National Institute of Health, Bethesda, U.S.A
2007-2008 日本國立國際醫療中心再生醫學研究所客座研究員
Visiting Fellow, International Medical Center of Japan
Department of Regenerative Medicine, Tokyo Japan
臨床職務經歷:
1992-1995 高雄醫學院附設醫院皮膚科住院醫師
1995-1996 高雄醫學院附設醫院皮膚科總住院醫師,
1996 迄今 中國醫藥大學附設醫院皮膚科主治醫師
2010 吳孟澤皮膚科診所主治醫師
學術職務經歷:
1998 July-2002 Feb 中國醫藥學院醫學系皮膚學科講師
2002 Feb 迄今 中國醫藥大學醫學系皮膚學科助理教授
2006 Jun 迄今 中國醫藥大學醫學系皮膚學科副教授 (副字034261)
行政職務經歷:
1998 July迄今 中國醫藥大學醫學系皮膚學科主任
2002 Feb 迄今 中國醫藥大學附設醫院皮膚科主任
2003 Dec -2006 台灣皮膚科醫學會副祕書長
2006迄今 台灣研究皮膚科醫學會理事
參與學會:
1995迄今 台灣皮膚科醫學會(The Chinese Dermatological Society, Taipei)
1997迄今 美國皮膚科醫學會 (The American Academy of Dermatology)
2001迄今 美國研究皮膚科學會 (The Society for Investigative Dermatology)
2003年起 美國免疫學家學會 (The American Association of Immunologists)
2006 年起 台灣研究皮膚科醫學會 (Taiwanese Society for Investigative Dermatology)
學術期刊編審:
台灣皮膚科醫學會(DERMATOLOGICA SINICA, SCIE)雜誌審查委員
台灣醫學會雜誌 (Journal of Formosan Medical Association, SCI) 論文審查
獸醫學期刊 (Journal of Veterinary Medicine, SCI) 論文審查
海洋藥物 (Marine Drugs, SCI) 論文審查
政府研究計畫主持人:
1998-1999 行政院衛生署中醫藥委員會(CCMP-88-RD-038) 計畫名稱: 腐盡生肌散促進傷口癒合作用機轉之研究
2002~2003 國科會(91-2314-B-039-026)計劃名稱: CCL21和 CCR7 對樹突細胞及T細胞移行及分化調控之研究
2002-2004 國科會 (91-2314-B-037-299) (共同主持人) Chemokine 受體與皮膚癌轉移之研究
2003-2004 國科會(92-2314-B-039-024) Overexpression of chemokine receptor CXCR4 in basal cell carcinoma
2003-2004 國科會(92-2314-B-039-025)Overexpression of Dihydrodiol Dehydrogenases in Skin Cancer
2003-2004 國科會(92-2314-B-037-113)(共同主持人): Expression and function of metalloproteinase in basal cell carcinoma
2004-2006 國家衛生研究院創新研究畫 (NHRI-EX93-9312BI) Cancer vaccination with double chemokines
2004-2005 國科會NSC-93-2314-B-039-007- CXCR4 之表現對基底細胞癌腫瘤增生以及基因調控影響之研究
2004-2007 國科會NSC-93-2745-B-039-002-URD皮膚癌及肺癌細胞 Hedgehog 訊息傳遞以及趨化激素受體表現之關連性
2005-2006 國科會 NSC- NSC 94-2314-B-039 -021 T淋巴球皮膚癌之皮膚趨向性研究
2007-2008 國科會 NSC 96-2314-B-039-014-皮膚 T 細胞淋巴瘤動物模式之建立
2008-2009 國科會 NSC 97-2314-B-039-025 趨化激素受體CCR3可能促進神經纖維瘤內肥大細胞之趨向性之研究
曾獲獎助及榮譽:
1997 國科會乙種研究獎勵
1998 國科會科技人員國外研究獎助
2003 獲選成為美國免疫學家學會 (The American Association of Immunologists) 會員
2003 台灣皮膚科文教基金會九十二年度論文獎
2007 武田科學振興獎學金 (Takeda Science Foundation) 獲獎
期刊論文著作
1. Meng-Tse Wu,Chao-Hsing Kao,Hsin-Su Yu: Huge squamous cell carcinoma : a case treated by continuous intralesional injection of bleomycin : Dermatol Sinica 12:37-46,1994
2. Hsin-Su Yu,Kee-Lung Chang,Chia-Li Yu,Hui-Fang LI,Meng-Tse Wu,Chieh-Shan Wu ,Ching-Shuang Wu: Effects of IgG antimelanocyte antibodies on T cell antigen expression in patient with active vitiligo The Japanese Journal of Dermatology (MI): 106:1811-1814,1996
3. Chang-Hai Tsai, Fuu-Jen Tsai,Ching-Tien Peng,Cheng-Chunee,Quey-Ching
Sheu,Meng-Tse Wu: Incontinentia pigmenti: Experience of senventeen cases.
Medical Journal of CMCH 198-201:1997
4. Hsin-Su Yu,Kee-Lung Chang,Chia-Li Yu,Hui-Fang LI,Meng-Tse Wu,Chieh-Shan Wu ,Ching-Shuang Wu: Alterations inIL-6,IL-8,GM-CSF,TNF-,and IFN- Release by Peripheral Mononuclear Cells in Patients with Active Vitiligo.Journal of the Investigative Dermatology (SCI, impact factor: 4.645): 108: 527-529,1997
5. Meng-Tse Wu,Chung-Hsing Chung,Hsin-Su Yu,Jia-Sheng Bair: Scleromyxedema with prominent linear eruption and polyclonal gammapathy Experimental and Clinical Dermatology (SCI, impact factor: 0.787) 22:110-111,1997
6. Lai SW, Chen YC, Tsai FJ, Wu MT, Peng CT, Lin CC, Tsai CH: Harlequin Ichthyosis : report of one case. Chung Hua Min Kuo Hsiao Erh Ko I Hsueh Hui Tsa Chih (MI). 39:412-4, 1998
7. Huang LL, Wu MT, Lee TL: Pacinian Neurofibroma of the scalp. Dermatologica Sinica. 17:78-81, 1999
8. Liu CH, Wu MT, Lin CI : Rhabdomyomatous mesenchymal hamartoma. Dermatologica Sinica. 18: 43-6,2000
9. Hidehisa Saeki, Meng-Tse Wu, Edit Olasz and Sam T. Hwang:A migratory population of skin-derived dendritic cells expresses CXCR5, responds to B lymphocyte chemoattractant in vitro, and co-localizes to B cell zones in lymph nodes in vivo European Journal of Immunology. (SCI, impact factor: 4.99). 30: 2808–2814. 2000
10. Meng-Tse Wu, Hui Fang, and Sam T. Hwang : CCR4 Mediates Antigen-Primed T Cell Binding to Activated Dendritic Cells The Journal of Immunology(SCI, impact factor: 7.065) 167: 4791–4795. 2001
11. Henry E. Wiley, Erik B. Gonzalez,Wusi Maki, Meng-T se Wu, Sam T.Hwang Expression of CC Chemokine Receptor-7 and RegionalLymph Node Metastasis of B16 Murine Melanoma. Journal of the National Cancer Institute (SCI, impact factor: 14.24) 93:1638-43. 2001
12. Meng-Tse Wu, Sam T. Hwang: : CXCR5-transduced bone marrow-derived dendritic cells traffic to B cell zones of lymph nodes and modify antigen-specific immune responses. The Journal of Immunology. (SCI, impact factor: 7.065) 168:5096-5102.2002
13. Gwo-Shing Chen, Hsin-Su Yu, Kuan-Chih Chow, Tze-Yi Lin, Mei-Pao Lu, Chao-Hong Liu, and Meng-Tse Wu (corresponding author): CXC chemokine receptor CXCR4 expression enhances tumorigenesis and angiogenesis of basal cell carcinoma. British Journal of Dermatology. (SCI, impact factor: 2.445)
154: 910-918. 2006
14. Gwo-Shing Chen, Mei-Pao Lu and Meng-Tse Wu (corresponding author): Differential Expression of Matrix Metalloproteinase-2 by Fibroblasts through co-cultures with Keratinocytes, Basal Cell Carcinoma, and Melanoma. Journal of Dermatology. (SCI) 33: 609-615. 2006
15. Kuan-Chih Chow, Mei-Pao Lub, and Meng-Tse Wu (corresponding author):: Expression of dihydrodiol dehydrogenase plays important roles in apoptosis- and drug-resistance of A431 squamous cell carcinoma. Journal of Dermatological Science (SCI, impact factor: 1.477) 41: 205-212. 2006
16. Shuen-Iu Hung, Wen-Hung Chung, Shiou-Hwa Jee, Wen-Chieh Chen,Yun-Ting Chang, Woan-Ruoh Lee, Shu-Ling Huh, Meng-Tse Wu, Gwo-Shing Chen, Tak-Wah Wong, Pa-Fan Hsia, Wei-Hsuan Chen, Han-Yu Shih, Wu-Hsiang Fang, Chun-Yu Wei, Yi-Hui Lou, Yau-Li Huang, Juei-Jueng Lin and Yuan-Tsong Chen: Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions. Pharmacogenetics and Genomics. 16: 297-306, 2006
17. Ming-Ya Mao, Hsu-Jung Hsieh, Tze-Yi Lin, Meng-Tse Wu (corresponding author): Chronic ulceration on the sole of an 81-year-old man. Dermatologica Sinica 26: 45-46, 2008
18. Chieh-Shan Wu, Sin-Ting Wang, Chai-Yu Liao, Meng-Tse Wu (corresponding author). Differential CCR4 Expression and Function in Cutaneous T-cell Lymphoma Cell Lines. Kaohsiung Journal of Medical Science 24: 577-90, 2008
19. Wei-Chun Tai, Hsu-Jung Hsieh, and Meng-Tse Wu (corresponding author). Hand, foot and mouth disease in a healthy adult caused by intrafamilial transmission of enterovirus 71. The British journal of dermatology 160, 890-892, 2009
20. Gwo-Shing Chen, Hui-Chuan Lin, and Meng-Tse Wu (corresponding author). Intense pulse light irradiation may reverse activator protein 1 expression induced by ultraviolet B
Journal of the American Academy of Dermatology (in press)
21. Wei-Chun Tai, Hsin-Pai Li,Tze-Yi. Chen-Yuan. Lin, and Meng-Tse Wu (corresponding author). Response of extranodal NK/T-cell lymphoma, nasal type, to interferon-, corticosteroid, and narrowband ultraviolet B phototherapy. Clinical and Experimental Dermatology (in press)
中國醫藥大學附設醫院皮膚科主治醫師/科主任
出生地: 嘉義市
研究興趣與方向: 皮膚科學, 雷射光療, 幹細胞再生醫學, 色素醫學 (白斑黑斑), 免疫疾病診療, 癌症診療
學歷:
1992 高雄醫學院醫學士
1997 高雄醫學院醫學研究所醫學碩士
2002 高雄醫學大學醫學研究所醫學博士
研究職務經歷:
1999-2001 美國國家衛生院國家癌症中心博士後研究
Visiting Fellow, National Cancer Institute,
National Institute of Health, Bethesda, U.S.A
2007-2008 日本國立國際醫療中心再生醫學研究所客座研究員
Visiting Fellow, International Medical Center of Japan
Department of Regenerative Medicine, Tokyo Japan
臨床職務經歷:
1992-1995 高雄醫學院附設醫院皮膚科住院醫師
1995-1996 高雄醫學院附設醫院皮膚科總住院醫師,
1996 迄今 中國醫藥大學附設醫院皮膚科主治醫師
2010 吳孟澤皮膚科診所主治醫師
學術職務經歷:
1998 July-2002 Feb 中國醫藥學院醫學系皮膚學科講師
2002 Feb 迄今 中國醫藥大學醫學系皮膚學科助理教授
2006 Jun 迄今 中國醫藥大學醫學系皮膚學科副教授 (副字034261)
行政職務經歷:
1998 July迄今 中國醫藥大學醫學系皮膚學科主任
2002 Feb 迄今 中國醫藥大學附設醫院皮膚科主任
2003 Dec -2006 台灣皮膚科醫學會副祕書長
2006迄今 台灣研究皮膚科醫學會理事
參與學會:
1995迄今 台灣皮膚科醫學會(The Chinese Dermatological Society, Taipei)
1997迄今 美國皮膚科醫學會 (The American Academy of Dermatology)
2001迄今 美國研究皮膚科學會 (The Society for Investigative Dermatology)
2003年起 美國免疫學家學會 (The American Association of Immunologists)
2006 年起 台灣研究皮膚科醫學會 (Taiwanese Society for Investigative Dermatology)
學術期刊編審:
台灣皮膚科醫學會(DERMATOLOGICA SINICA, SCIE)雜誌審查委員
台灣醫學會雜誌 (Journal of Formosan Medical Association, SCI) 論文審查
獸醫學期刊 (Journal of Veterinary Medicine, SCI) 論文審查
海洋藥物 (Marine Drugs, SCI) 論文審查
政府研究計畫主持人:
1998-1999 行政院衛生署中醫藥委員會(CCMP-88-RD-038) 計畫名稱: 腐盡生肌散促進傷口癒合作用機轉之研究
2002~2003 國科會(91-2314-B-039-026)計劃名稱: CCL21和 CCR7 對樹突細胞及T細胞移行及分化調控之研究
2002-2004 國科會 (91-2314-B-037-299) (共同主持人) Chemokine 受體與皮膚癌轉移之研究
2003-2004 國科會(92-2314-B-039-024) Overexpression of chemokine receptor CXCR4 in basal cell carcinoma
2003-2004 國科會(92-2314-B-039-025)Overexpression of Dihydrodiol Dehydrogenases in Skin Cancer
2003-2004 國科會(92-2314-B-037-113)(共同主持人): Expression and function of metalloproteinase in basal cell carcinoma
2004-2006 國家衛生研究院創新研究畫 (NHRI-EX93-9312BI) Cancer vaccination with double chemokines
2004-2005 國科會NSC-93-2314-B-039-007- CXCR4 之表現對基底細胞癌腫瘤增生以及基因調控影響之研究
2004-2007 國科會NSC-93-2745-B-039-002-URD皮膚癌及肺癌細胞 Hedgehog 訊息傳遞以及趨化激素受體表現之關連性
2005-2006 國科會 NSC- NSC 94-2314-B-039 -021 T淋巴球皮膚癌之皮膚趨向性研究
2007-2008 國科會 NSC 96-2314-B-039-014-皮膚 T 細胞淋巴瘤動物模式之建立
2008-2009 國科會 NSC 97-2314-B-039-025 趨化激素受體CCR3可能促進神經纖維瘤內肥大細胞之趨向性之研究
曾獲獎助及榮譽:
1997 國科會乙種研究獎勵
1998 國科會科技人員國外研究獎助
2003 獲選成為美國免疫學家學會 (The American Association of Immunologists) 會員
2003 台灣皮膚科文教基金會九十二年度論文獎
2007 武田科學振興獎學金 (Takeda Science Foundation) 獲獎
期刊論文著作
1. Meng-Tse Wu,Chao-Hsing Kao,Hsin-Su Yu: Huge squamous cell carcinoma : a case treated by continuous intralesional injection of bleomycin : Dermatol Sinica 12:37-46,1994
2. Hsin-Su Yu,Kee-Lung Chang,Chia-Li Yu,Hui-Fang LI,Meng-Tse Wu,Chieh-Shan Wu ,Ching-Shuang Wu: Effects of IgG antimelanocyte antibodies on T cell antigen expression in patient with active vitiligo The Japanese Journal of Dermatology (MI): 106:1811-1814,1996
3. Chang-Hai Tsai, Fuu-Jen Tsai,Ching-Tien Peng,Cheng-Chunee,Quey-Ching
Sheu,Meng-Tse Wu: Incontinentia pigmenti: Experience of senventeen cases.
Medical Journal of CMCH 198-201:1997
4. Hsin-Su Yu,Kee-Lung Chang,Chia-Li Yu,Hui-Fang LI,Meng-Tse Wu,Chieh-Shan Wu ,Ching-Shuang Wu: Alterations inIL-6,IL-8,GM-CSF,TNF-,and IFN- Release by Peripheral Mononuclear Cells in Patients with Active Vitiligo.Journal of the Investigative Dermatology (SCI, impact factor: 4.645): 108: 527-529,1997
5. Meng-Tse Wu,Chung-Hsing Chung,Hsin-Su Yu,Jia-Sheng Bair: Scleromyxedema with prominent linear eruption and polyclonal gammapathy Experimental and Clinical Dermatology (SCI, impact factor: 0.787) 22:110-111,1997
6. Lai SW, Chen YC, Tsai FJ, Wu MT, Peng CT, Lin CC, Tsai CH: Harlequin Ichthyosis : report of one case. Chung Hua Min Kuo Hsiao Erh Ko I Hsueh Hui Tsa Chih (MI). 39:412-4, 1998
7. Huang LL, Wu MT, Lee TL: Pacinian Neurofibroma of the scalp. Dermatologica Sinica. 17:78-81, 1999
8. Liu CH, Wu MT, Lin CI : Rhabdomyomatous mesenchymal hamartoma. Dermatologica Sinica. 18: 43-6,2000
9. Hidehisa Saeki, Meng-Tse Wu, Edit Olasz and Sam T. Hwang:A migratory population of skin-derived dendritic cells expresses CXCR5, responds to B lymphocyte chemoattractant in vitro, and co-localizes to B cell zones in lymph nodes in vivo European Journal of Immunology. (SCI, impact factor: 4.99). 30: 2808–2814. 2000
10. Meng-Tse Wu, Hui Fang, and Sam T. Hwang : CCR4 Mediates Antigen-Primed T Cell Binding to Activated Dendritic Cells The Journal of Immunology(SCI, impact factor: 7.065) 167: 4791–4795. 2001
11. Henry E. Wiley, Erik B. Gonzalez,Wusi Maki, Meng-T se Wu, Sam T.Hwang Expression of CC Chemokine Receptor-7 and RegionalLymph Node Metastasis of B16 Murine Melanoma. Journal of the National Cancer Institute (SCI, impact factor: 14.24) 93:1638-43. 2001
12. Meng-Tse Wu, Sam T. Hwang: : CXCR5-transduced bone marrow-derived dendritic cells traffic to B cell zones of lymph nodes and modify antigen-specific immune responses. The Journal of Immunology. (SCI, impact factor: 7.065) 168:5096-5102.2002
13. Gwo-Shing Chen, Hsin-Su Yu, Kuan-Chih Chow, Tze-Yi Lin, Mei-Pao Lu, Chao-Hong Liu, and Meng-Tse Wu (corresponding author): CXC chemokine receptor CXCR4 expression enhances tumorigenesis and angiogenesis of basal cell carcinoma. British Journal of Dermatology. (SCI, impact factor: 2.445)
154: 910-918. 2006
14. Gwo-Shing Chen, Mei-Pao Lu and Meng-Tse Wu (corresponding author): Differential Expression of Matrix Metalloproteinase-2 by Fibroblasts through co-cultures with Keratinocytes, Basal Cell Carcinoma, and Melanoma. Journal of Dermatology. (SCI) 33: 609-615. 2006
15. Kuan-Chih Chow, Mei-Pao Lub, and Meng-Tse Wu (corresponding author):: Expression of dihydrodiol dehydrogenase plays important roles in apoptosis- and drug-resistance of A431 squamous cell carcinoma. Journal of Dermatological Science (SCI, impact factor: 1.477) 41: 205-212. 2006
16. Shuen-Iu Hung, Wen-Hung Chung, Shiou-Hwa Jee, Wen-Chieh Chen,Yun-Ting Chang, Woan-Ruoh Lee, Shu-Ling Huh, Meng-Tse Wu, Gwo-Shing Chen, Tak-Wah Wong, Pa-Fan Hsia, Wei-Hsuan Chen, Han-Yu Shih, Wu-Hsiang Fang, Chun-Yu Wei, Yi-Hui Lou, Yau-Li Huang, Juei-Jueng Lin and Yuan-Tsong Chen: Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions. Pharmacogenetics and Genomics. 16: 297-306, 2006
17. Ming-Ya Mao, Hsu-Jung Hsieh, Tze-Yi Lin, Meng-Tse Wu (corresponding author): Chronic ulceration on the sole of an 81-year-old man. Dermatologica Sinica 26: 45-46, 2008
18. Chieh-Shan Wu, Sin-Ting Wang, Chai-Yu Liao, Meng-Tse Wu (corresponding author). Differential CCR4 Expression and Function in Cutaneous T-cell Lymphoma Cell Lines. Kaohsiung Journal of Medical Science 24: 577-90, 2008
19. Wei-Chun Tai, Hsu-Jung Hsieh, and Meng-Tse Wu (corresponding author). Hand, foot and mouth disease in a healthy adult caused by intrafamilial transmission of enterovirus 71. The British journal of dermatology 160, 890-892, 2009
20. Gwo-Shing Chen, Hui-Chuan Lin, and Meng-Tse Wu (corresponding author). Intense pulse light irradiation may reverse activator protein 1 expression induced by ultraviolet B
Journal of the American Academy of Dermatology (in press)
21. Wei-Chun Tai, Hsin-Pai Li,Tze-Yi. Chen-Yuan. Lin, and Meng-Tse Wu (corresponding author). Response of extranodal NK/T-cell lymphoma, nasal type, to interferon-, corticosteroid, and narrowband ultraviolet B phototherapy. Clinical and Experimental Dermatology (in press)
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